Protamine Sulfate

The antidote for heparin is Protamine Sulfate. If you give them protamine it helps bind up the heparin and eliminate it through the kidneys. Even though it’s an antidote, you can’t overdo the antidote because protamine sulfate is also an anticoagulant. If you give them too much protamine, they will actually bleed and the antidote now is to give them heparin.

Binds excess heparin
1mg binds 100 units of heparin
Excess protamine has anticoagulant properties

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